Description:
A gene that
makes one of the proteins in an enzyme called PI3K, which
is involved in many important functions in a cell.
Mutations (changes) in the PIK3CA gene may cause the PI3K
enzyme to become overactive, which may cause cancer cells
to grow. PIK3CA gene mutations have been found in many
types of cancer, including cancers of the breast, lung,
ovary, stomach, brain, colon, and rectum. They have also
been found in some genetic conditions.
