Term: bispecific fusion protein

Pronunciation: (BY-speh-SIH-fik FYOO-zhun PROH-teen)

Description:

A protein made in the laboratory that can bind to two different molecules on two different cells at the same time. For example, a bispecific fusion protein may bind to a certain molecule on cancer cells and, at the same time, bind to a different molecule on T cells (a type of immune cell). This helps the body’s T cells get close enough to the cancer cells to kill them. Bispecific fusion proteins may be used as a type of immunotherapy to treat some types of cancer.