Description:
A substance made in the laboratory that can bind to two target proteins on the surface of different cells. For example, a BiTE may bind to a certain protein on healthy T cells (a type of immune cell) and, at the same time, to a different protein on cancer cells. This brings the T cells and cancer cells close together so the T cells can more effectively kill the cancer cells. Some BiTEs are being used to treat certain types of cancer, including acute lymphoblastic leukemia, multiple myeloma, lymphoma, and small cell lung cancer. They are a type of targeted therapy. Also called bispecific T-cell engager.
