Binimetinib

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 (BIH-nee-MEH-tih-nib)

This page contains brief information about binimetinib and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.

US Brand Name(s)
Mektovi
FDA Approved
Yes

FDA label information for this drug is available at DailyMed.

Use in Cancer

Binimetinib is approved to be used with encorafenib to treat patients whose cancer has a certain mutation in the BRAF gene, including:

  • Melanoma that cannot be removed by surgery or has spread to other parts of the body.
  • Non-small cell lung cancer. It is in adults whose cancer has spread to other parts of the body.

Binimetinib is also being studied in the treatment of other types of cancer.

More About Binimetinib

Definition from the NCI Drug Dictionary – Detailed scientific definition and other names for this drug.

More About Binimetinib – A lay language summary of important information about this drug that may include the following:

  • warnings about this drug,
  • what this drug is used for and how it is used,
  • what you should tell your doctor before using this drug,
  • what you should know about this drug before using it,
  • other drugs that may interact with this drug, and
  • possible side effects.

Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.

Research Results and Related Resources

Androgen Receptor May Explain Sex Differences in Melanoma Treatment Response

Targeted Therapy to Treat Cancer

Clinical Trials Accepting Patients

Find Clinical Trials for Binimetinib – Check for trials from NCI’s list of cancer clinical trials now accepting patients.