(brek-suh-KAB-tuh-jeen aw-toh-LOO-sel)
This page contains brief information about brexucabtagene autoleucel (Tecartus) and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.
FDA label information for this drug is available at DailyMed.
Use in Cancer
Brexucabtagene autoleucel is approved to treat adults with:
- Mantle cell lymphoma that has come back or does not respond to treatment.¹
- Precursor B lymphoblastic leukemia (a type of acute lymphoblastic leukemia) that has come back or does not respond to treatment.
¹This use is approved under FDA’s Accelerated Approval Program. As a condition of approval, confirmatory trial(s) must show that brexucabtagene autoleucel provides a clinical benefit in these patients.
Brexucabtagene autoleucel is only available as part of a special program called Tecartus REMS (Risk Evaluation and Mitigation Strategies).
Brexucabtagene autoleucel is also being studied in the treatment of other types of cancer.
More About Brexucabtagene Autoleucel
Definition from the NCI Drug Dictionary – Detailed scientific definition and other names for this drug.
More About Brexucabtagene Autoleucel – A lay language summary of important information about this drug that may include the following:
- warnings about this drug,
- what this drug is used for and how it is used,
- what you should tell your doctor before using this drug,
- what you should know about this drug before using it,
- other drugs that may interact with this drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.
Research Results and Related Resources
Tecartus Becomes First CAR T-Cell Therapy Approved for Adults with ALL
CAR T Cells: Engineering Patients’ Immune Cells to Treat Their Cancers
Clinical Trials Accepting Patients
Find Clinical Trials for Brexucabtagene Autoleucel – Check for trials from NCI’s list of cancer clinical trials now accepting patients.
