Drugs Approved for Conditions Related to Cancer

People with cancer may have other conditions caused by the cancer or its treatment. Drugs approved by the FDA for some of these cancer-related conditions are listed on this page. The drug names link to NCI’s Cancer Drug Information summaries that provide information about these drugs. There may be other drugs used in these conditions that are not listed here.

Actinic Keratosis

• Aminolevulinic Acid (Ameluz, Levulan Kerastick)
• Fluorouracil (5-FU) Topical (Carac, Efudex, Fluoroplex, Tolak)
• Imiquimod (Aldara, Zyclara)

Aggressive Systemic Mastocytosis

• Imatinib Mesylate (Gleevec)
• Midostaurin (Rydapt)

Anemia (Low Red Blood Cells)

• Darbepoetin Alfa (Aranesp)
• Dexamethasone
• Epoetin Alfa (Epogen, Procrit, Retacrit)
• Lenalidomide (Revlimid)
• Luspatercept-aamt (Reblozyl)
• Prednisone

Carcinoid Syndrome

• Lanreotide Acetate (Somatuline Depot)

Cardiac Toxicity (Heart Side Effects)

• Dexrazoxane Hydrochloride (Zinecard)
• Uridine Triacetate (Vistogard)

Condyloma Acuminata (Genital Warts)

• Imiquimod (Aldara, Zyclara)
• Recombinant Human Papillomavirus (HPV) Nonavalent Vaccine (Gardasil 9)
• Recombinant Human Papillomavirus (HPV) Quadrivalent Vaccine (Gardasil)
• Recombinant Interferon Alfa-2b (Intron A)

Constipation

• Methylnaltrexone Bromide (Relistor)

Cytokine Release Syndrome

Tocilizumab (Actemra)

Drug Extravasation (Drug Leakage in Tissues)

• Dexrazoxane Hydrochloride (Totect)

Drug Toxicity (Severe Side Effects)

• Amifostine (Ethyol)—for Cisplatin Toxicity
• Dexamethasone
• Dexrazoxane Hydrochloride (Zinecard)—for Doxorubicin Toxicity
• Glucarpidase (Voraxaze)—for Methotrexate Toxicity
• Prednisone
• Uridine Triacetate (Vistogard)—for Capecitabine or Fluorouracil Toxicity

Hemophagocytic Lymphohistiocytosis

• Emapalumab-lzsg (Gamifant)

Hemorrhagic Cystitis (Bleeding in the Bladder)

• Mesna (Mesnex)

Hepatic Veno-occlusive Disease (Blocked Liver Veins)

• Defibrotide Sodium (Defitelio)

Hypercalcemia of Malignancy (High Blood Calcium)

• Denosumab (Xgeva)
• Dexamethasone
• Pamidronate Disodium (Aredia)
• Prednisone
• Zoledronic Acid (Zometa)

Malignant Effusion

• Bleomycin
• Talc (Sterile Talc Powder, Sclerosol Intrapleural Aerosol, Steritalc)
• Thiotepa (Tepadina)

Mucositis (Inflamed Mucous Membranes)

• Palifermin (Kepivance)

Nausea and Vomiting

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• Akynzeo (Netupitant and Palonosetron Hydrochloride)

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• Aprepitant (Cinvanti, Emend)
• Granisetron (Sancuso, Sustol)
• Granisetron Hydrochloride
• Netupitant and Palonosetron Hydrochloride (Akynzeo)
• Ondansetron Hydrochloride (Zofran)
• Palonosetron Hydrochloride (Aloxi)
• Rolapitant Hydrochloride (Varubi)

Neurotoxicity (Nervous System Side Effects)

• Uridine Triacetate (Vistogard)

Neutropenia (Low Blood Neutrophils)

• Filgrastim (Granix, Neupogen, Nivestym, Zarxio)
• Pegfilgrastim (Fulphila, Neulasta, Nyvepria, Udencyca, Ziextenzo)

Osteoporosis (Loss of Bone Density)

• Denosumab (Prolia)
• Raloxifene Hydrochloride (Evista)

Paroxysmal Nocturnal Hemoglobinuria

• Ravulizumab-cwvz (Ultomiris)

Renal Toxicity (Kidney Side Effects)

• Amifostine (Ethyol)

Skin Changes Due to Cutaneous Metastases

• Bexarotene (Targretin)

Thrombocytopenia (Low Blood Platelets)

• Caplacizumab-yhdp (Cablivi)
• Dexamethasone
• Eltrombopag Olamine (Promacta)
• Fostamatinib Disodium (Tavalisse)
• Prednisone
• Romiplostim (Nplate)

Tumor Lysis Syndrome (Cell Breakdown and Organ Damage)

• Rasburicase (Elitek)

Xerostomia (Dry Mouth)

• Amifostine (Ethyol)